abstract：:With the paradigm shift from the reduction of morbidity and mortality to the interruption of transmission, the focus of malaria control broadens from symptomatic infections in children ≤5 years of age to include asymptomatic infections in older children and adults. In addition, as control efforts intensify and the num...

journal_title：Acta tropica

authors： Doumbia SO,Ndiaye D,Koita OA,Diakité M,Nwakanma D,Coulibaly M,Traoré SF,Keating J,Milner DA Jr,Ndiaye JL,Sene PD,Ahouidi A,Dieye TN,Gaye O,Okebe J,Ceesay SJ,Ngwa A,Oriero EC,Konaté L,Sy N,Jawara M,Faye O,Kéita

更新日期：2012-03-01 00:00:00

abstract：:To determine the infestation and trypanosome infection of triatomines captured in Mauritia flexuosa palm trees across its geographic distribution in the Brazilian savanna (Cerrado), we sampled 42 localities in eight states and in the Federal District, Brazil, between July 2005 and January 2010. Overall, 2154 specimens...

journal_title：Acta tropica

authors： Gurgel-Gonçalves R,Cura C,Schijman AG,Cuba CA

更新日期：2012-02-01 00:00:00

abstract：:Bashagard is an important malaria endemic area in south of Iran. An epidemiological and entomological survey was performed during 2002-2010. The aim of study was to determine malaria situation, species composition of anopheline mosquitoes and susceptibility status of main vectors to insecticides/larvicides. A total of...

journal_title：Acta tropica

authors： Hanafi-Bojd AA,Vatandoost H,Oshaghi MA,Haghdoost AA,Shahi M,Sedaghat MM,Abedi F,Yeryan M,Pakari A

更新日期：2012-02-01 00:00:00

abstract：:The ability of Phlebotomus langeroni to successfully acquire and transmit Leishmania infantum MON-98 to hamsters was demonstrated. Sand flies and Leishmania both originated from an infantile visceral leishmaniasis focus in El Agamy Egypt. P. langeroni females were infected by feeding on lesions of needle-inoculated ha...

journal_title：Acta tropica

authors： El Sawaf BM,Doha SA,Imam MI

更新日期：2012-01-01 00:00:00

abstract：:Heme (iron protoporphyrin IX) is an important molecule involved in many biological reactions, including oxygen transport, respiration, photosynthesis and drug detoxification. Trypanosoma cruzi parasites, the etiological agent of Chagas' disease, take up heme from the environment to supply their nutritional needs becau...

journal_title：Acta tropica

authors： Cupello MP,Souza CF,Buchensky C,Soares JB,Laranja GA,Coelho MG,Cricco JA,Paes MC

更新日期：2011-12-01 00:00:00

abstract：:The rapid, accurate diagnosis of Plasmodium spp. is essential for the effective control of malaria, especially in asymptomatic infections. In this study, we developed a sensitive, genus-specific, real-time quantitative PCR assay. It was compared with the microscopic examination of Giemsa-stained blood smears and two d...

journal_title：Acta tropica

authors： Hwang SY,Kim SH,Lee GY,Hang VT,Moon CS,Shin JH,Koo WL,Kim SY,Park HJ,Park HO,Kho WG

更新日期：2011-10-01 00:00:00

abstract：:We analyzed the spatial distribution of human cases of scrub typhus on the main island of Taiwan from 2003 to 2008 and implemented an island-wide survey of scrub typhus vectors (trombiculid chiggers) in 2007 and 2008. The standardized incidence rate 'SIR' incorporating inter-district variations in population, gender a...

journal_title：Acta tropica

authors： Kuo CC,Huang JL,Ko CY,Lee PF,Wang HC

更新日期：2011-10-01 00:00:00

abstract：:Malaria is second only to tuberculosis as the leading cause of morbidity and mortality as a consequence of a single infectious agent. Much of the pathology of malaria arises from the inappropriate or excessive immune response mounted by the host in an attempt to eliminate the parasite. We here report the inflammatory ...

journal_title：Acta tropica

authors： Lacerda-Queiroz N,Lima OC,Carneiro CM,Vilela MC,Teixeira AL,Teixeira-Carvalho A,Araújo MS,Martins-Filho OA,Braga EM,Carvalho-Tavares J

更新日期：2011-10-01 00:00:00

abstract：:The internal classification of the cosmopolitan and medically important genus Culex is thoroughly reviewed and updated to reflect the multitude of taxonomic changes and concepts which have been published since the classification was last compiled by Edwards in 1932. Both formal and informal taxa are included. The clas...

journal_title：Acta tropica

authors： Harbach RE

更新日期：2011-10-01 00:00:00

abstract：:A parasitological survey was conducted among children and adolescents in the municipality of Jaboatão dos Guararapes, Brazil to describe the occurrence and spatial distribution of lymphatic filariasis. Microfilaraemia was investigated through the thick smear technique, using 50 μl of capillary blood that was collected...

journal_title：Acta tropica

authors： Brandão E,Bonfim C,Cabral D,Lima JL,Aguiar-Santos AM,Maciel A,Medeiros Z

更新日期：2011-10-01 00:00:00

abstract：:Disease control programmes are an intrinsic part of health systems. Neglected tropical disease (NTD) control is a clear case in point. While there is a growing consensus that NTD control and health services are linked, with important mutual impacts, little is known of what actually happens at the interface between the...

journal_title：Acta tropica

authors： Marchal B,Van Dormael M,Pirard M,Cavalli A,Kegels G,Polman K

更新日期：2011-09-01 00:00:00

abstract：:Soil-transmitted helminthiasis (STH) occur throughout the developing world and remain a major public health problem in the poorest communities with enormous consequences on health and development of school-aged and preschool children. The extent of the problem has long been neglected because these diseases rarely kill...

journal_title：Acta tropica

authors： Tchuem Tchuenté LA

更新日期：2011-09-01 00:00:00

abstract：:Mansonella perstans is a vector-borne human filarial nematode, transmitted by tiny blood-sucking flies (biting midges). It is widespread in many parts of Sub-Saharan Africa and also occurs in parts of Central and South America. Despite the commonness of this parasite very few studies have been carried out on its epide...

journal_title：Acta tropica

authors： Simonsen PE,Onapa AW,Asio SM

更新日期：2011-09-01 00:00:00

abstract：:Leishmaniasis due to Leishmania infantum (syn. L. chagasi) infection is a zoonotic disease present mainly in Mediterranean basin, central Asia and Brazil. Besides a limited number of human cases of clinical visceral leishmaniasis, a great number of infections remains asymptomatic. In this review, the prevalence of asy...

journal_title：Acta tropica

authors： Michel G,Pomares C,Ferrua B,Marty P

更新日期：2011-08-01 00:00:00

abstract：:Although long considered a non-pathogenic protozoan, Giardia lamblia is now a well recognized cause of abdominal discomfort, diarrhoea and failure-to-thrive in children. The overall prevalence of this infection in Cuban population is about 7.2%; however, higher prevalences have been found among young children attendin...

journal_title：Acta tropica

authors： Escobedo AA,Almirall P,Alfonso M,Avila I,Cimerman S,Salazar Y,Dawkins IV,García RM

更新日期：2011-08-01 00:00:00

abstract：:Chronic malaria severely affects the immune system and causes polyclonal B-cell activation, as evidenced by the presence of hypergammaglobulinemia, elevated levels of autoantibodies, loss of B-cell memory and the frequent occurrence of Burkitt's lymphomas (BL) in children living in malaria endemic areas. Previous stud...

journal_title：Acta tropica

authors： Simone O,Bejarano MT,Pierce SK,Antonaci S,Wahlgren M,Troye-Blomberg M,Donati D

更新日期：2011-08-01 00:00:00

abstract：:In Triatominae, female fecundity and fertility may be affected by age, adult nutritional status (i.e., blood meal source and amount of blood ingested) and number of matings. Triatoma infestans (Klug) is the main vector of Chagas disease in southern South America and considering that reproductive success is intimately ...

journal_title：Acta tropica

authors： Nattero J,Leonhard G,Rodríguez CS,Crocco L

更新日期：2011-08-01 00:00:00

abstract：:This study was conducted to determine the effects of increased water temperatures on the development of Aedes aegypti immatures under laboratory conditions in Trinidad, West Indies using temperature regulated water baths to cover a range of temperatures from 24-25°C to 34-35°C at a relative humidity of 80%. Two experi...

journal_title：Acta tropica

authors： Mohammed A,Chadee DD

更新日期：2011-07-01 00:00:00

abstract：:Plasmodium vivax is still the more prevalent human Plasmodium outside Africa and despite this fact, there is still a deep lack of knowledge on its biology. Metacaspases are cysteine proteases related to metazoan caspases, involved in programmed cell death. Here, we have characterized the P. vivax metacaspase 1 gene in...

journal_title：Acta tropica

authors： Rezanezhad H,Menegon M,Sarkari B,Hatam GR,Severini C

更新日期：2011-07-01 00:00:00

abstract：:The increasing spread of multi-drug resistant malaria in African highlands has highlighted the importance of malaria suppression through vector control. Its historical success has meant that larval control has been proposed as part of an integrated malaria vector control program. Due to high operation costs, larval co...

journal_title：Acta tropica

authors： Li L,Bian L,Yakob L,Zhou G,Yan G

更新日期：2011-07-01 00:00:00

abstract：:The murine monoclonal anti-idiotypic antibody NP30 is a promising therapeutic antibody against Schistosoma japonicum. However, the immunogenicity of murine NP30 limits its further study and application in humans. Here the chimeric Fab of NP30 (chFab-NP30) comprising the variable regions of murine NP30 and constant reg...

journal_title：Acta tropica

authors： Xu J,Zhu XJ,Li YH,Dai Y,Zhu YC,Zheng J,Feng ZQ,Guan XH

更新日期：2011-05-01 00:00:00

abstract：:Culex quinquefasciatus Say (Diptera: Culicidae) is a widely distributed mosquito vector species in India and also in other tropical regions of the world. This species is implicated in the transmission of lymphatic filariasis in many countries. This species is reported to be widely resistant to insecticides of differen...

journal_title：Acta tropica

authors： Raghavendra K,Barik TK,Bhatt RM,Srivastava HC,Sreehari U,Dash AP

更新日期：2011-04-01 00:00:00

abstract：:The persistence of Trypanosoma cruzi in seropositive individuals, previously diagnosed as chronic chagasic patients (CCP), was detected for the first time in biopsies taken from gingival inflammatory foci processed by polymerase chain reaction (PCR). Seven out of 31 (22.5%) gum samples from selected unquestionably CCP...

journal_title：Acta tropica

authors： Añez N,Crisante G,Caraballo F,Delgado W,Parada H

更新日期：2011-03-01 00:00:00

abstract：:Treatment failure of chloroquine for Plasmodium vivax infection has increased in endemic countries. However, the molecular mechanisms for resistance and in vitro susceptibility of P. vivax to chloroquine remain elusive. We investigated the prevalence of mutations in the pvmdr1 and pvcrt-o genes, and the copy number of...

journal_title：Acta tropica

authors： Lu F,Lim CS,Nam DH,Kim K,Lin K,Kim TS,Lee HW,Chen JH,Wang Y,Sattabongkot J,Han ET

更新日期：2011-02-01 00:00:00

abstract：:Chagas disease is a tropical parasitic disease endemic to Latin America which affects more than 10 million people, and kills more than 15,000 people each year. This condition, caused by the protozoan parasite Trypanosoma cruzi, is principally transmitted by kissing bugs (Triatominae). In Bolivia, recent reports by the...

journal_title：Acta tropica

authors： Depickère S,Durán P,López R,Chávez T

更新日期：2011-02-01 00:00:00

abstract：:In mid-August 2004, an outbreak of a previously unknown fatal disease of camels was reported to Kassala State veterinary authorities. Several areas in the state were visited during August-October 2004 to collect epidemiological data and specimens for diagnosis. Clinically the disease was characterized by sudden death ...

journal_title：Acta tropica

authors： Khalafalla AI,Saeed IK,Ali YH,Abdurrahman MB,Kwiatek O,Libeau G,Obeida AA,Abbas Z

更新日期：2010-11-01 00:00:00

abstract：:A field trial was conducted on the efficacy of Interceptor nets-a long-lasting insecticidal net (LLN) factory treated with alphacypermethrin 0.667% (w/w) corresponding to 200mg/m(2), against malaria vectors Anopheles culicifacies and Anopheles fluviatilis in one of the highly endemic areas of Orissa. The study area co...

journal_title：Acta tropica

authors： Sharma SK,Upadhyay AK,Haque MA,Tyagi PK,Raghavendra K,Dash AP

更新日期：2010-10-01 00:00:00

abstract：:Controlling dengue fever in Australia and internationally, relies heavily upon the actions of residents as well as community education and awareness of the risks. Although it has been well established in medical anthropology that the success of health interventions is highly dependent upon a clear grasp of lay knowled...

journal_title：Acta tropica

authors： McNaughton D,Clough A,Johnson P,Ritchie S,O'Neill S

更新日期：2010-10-01 00:00:00

abstract：:A study of the natural infection of phlebotomine sand flies by Leishmania (Leishmania) infantum was conducted in an area of visceral leishmaniasis in São Vicente Férrer, located in the northern part of the Atlantic rain forest region in the State of Pernambuco, Brazil. In a previous study, Migonemyia migonei have been...

journal_title：Acta tropica

authors： de Carvalho MR,Valença HF,da Silva FJ,de Pita-Pereira D,de Araújo Pereira T,Britto C,Brazil RP,Brandão Filho SP

更新日期：2010-10-01 00:00:00

abstract：:Tropomyosins of invertebrates are pan-allergens responsible for wide spread allergic reactions against seafood and arthropods. As invertebrate tropomyosins are highly conserved, helminth tropomyosins are likely to show properties similar to these medically important allergens. Studies with a monoclonal antibody, NR1, ...

journal_title：Acta tropica

authors： Sereda MJ,Hartmann S,Büttner DW,Volkmer R,Hovestädt M,Brattig N,Lucius R

更新日期：2010-10-01 00:00:00

abstract：:Microtus fortis is a naturally resistant vertebrate host of Schistosoma japonicum by preventing completion of parasite's life cycle. Sera of M. fortis were found to have anti-schistosome effect in vitro and in vivo. In order to identify genes associated with the anti-schistosome effect of M. fortis, we screened a M. f...

journal_title：Acta tropica

authors： Gong Q,Cheng G,Qin ZQ,Xiong DH,Yu YJ,Zeng QR,Hu WX

更新日期：2010-09-01 00:00:00

abstract：:The effect of concomitant infection with schistosomes, Plasmodium falciparum and soil transmitted helminths (STHs) on anaemia was determined in 609 Zimbabwean primary school children. P. falciparum, haemoglobin levels and serum ferritin were determined from venous blood. Kato Katz, formal ether concentration and urine...

journal_title：Acta tropica

authors： Midzi N,Mtapuri-Zinyowera S,Mapingure MP,Sangweme D,Chirehwa MT,Brouwer KC,Mudzori J,Hlerema G,Mutapi F,Kumar N,Mduluza T

更新日期：2010-07-01 00:00:00

abstract：:Transfusion transmitted Chagas disease was recognized as a medical problem more than 50 years ago. However, little attention was paid to it by Transfusion Medicine, medical authorities or regulatory agencies as a major problem and threat (especially after the advent of HIV/AIDS); perhaps because it was mainly restrict...

journal_title：Acta tropica

authors： Wendel S

更新日期：2010-07-01 00:00:00

abstract：:Malaria kills more than a million people a year, causes malady in about three hundred million people and poses risk to approximately 40% of the world's population living in malarious countries. This disease is re-emerging mainly due to the development of drug-resistant parasites and insecticide-resistant mosquitoes. T...

journal_title：Acta tropica

authors： Tsuboi T,Takeo S,Arumugam TU,Otsuki H,Torii M

更新日期：2010-06-01 00:00:00

abstract：:Resistance to chloroquine (CQ) in Plasmodium falciparum has a major impact on malaria control worldwide. To gain insight into early parasite stress response, mRNA expression profiles were determined for a set of 10 antioxidant defence genes in synchronized CQ-sensitive (3D7) and CQ-resistant (Dd2) clones under transie...

journal_title：Acta tropica

authors： Nogueira F,Diez A,Radfar A,Pérez-Benavente S,do Rosario VE,Puyet A,Bautista JM

更新日期：2010-05-01 00:00:00

abstract：:Glutathione transferases (GSTs) are believed to be a major detoxification system in helminths. We describe the expression and functional analysis of EgGST, a cytosolic GST from Echinococcus granulosus, related to the Mu-class of mammalian enzymes. EgGST was produced as an enzymatically active dimeric protein (rEgGST),...

journal_title：Acta tropica

authors： Harispe L,García G,Arbildi P,Pascovich L,Chalar C,Zaha A,Fernandez C,Fernandez V

更新日期：2010-04-01 00:00:00

abstract：:Cystic echinococcosis (CE) or hydatid disease is known to be cosmopolitan in its global distribution, while alveolar echinococcosis (AE) is a much rarer though more pathogenic hepatic parasitic disease restricted to the northern hemisphere. Both forms of human echinococcosis are known to occur on the Tibetan Plateau, ...

journal_title：Acta tropica

authors： Li T,Chen X,Zhen R,Qiu J,Qiu D,Xiao N,Ito A,Wang H,Giraudoux P,Sako Y,Nakao M,Craig PS

更新日期：2010-03-01 00:00:00

abstract：:We compared age-related seroprevalence of Trypanosoma cruzi infection with history of vector control interventions and social and ecological changes in three historically endemic departments of Cordoba province, Argentina, covering an area of 42,600 km(2) of the Gran Chaco region. Using a cross sectional design, blood...

journal_title：Acta tropica

authors： Moreno ML,Moretti E,Basso B,Céspedes MF,Catalá SS,Gorla DE

更新日期：2010-03-01 00:00:00

abstract：:The complete life cycle of the trematode Ascocotyle (Phagicola) longa (Digenea: Heterophyidae) is elucidated by natural observation validated by experimental infections. The natural first intermediate host of A. (P.) longa, an agent of human heterophyiasis in Brazil, is the cochliopid snail Heleobia australis (new fir...

journal_title：Acta tropica

authors： Simões SB,Barbosa HS,Santos CP

更新日期：2010-03-01 00:00:00

abstract：:Malaria is one of the major causes of morbidity and mortality worldwide. The major factor which has aggravated the situation is the emergence of multidrug resistant Plasmodium falciparum malaria. To successfully deal with the problem, thorough understanding of the molecular bases for reduced parasite sensitivity to ex...

journal_title：Acta tropica

authors： Chaijaroenkul W,Wisedpanichkij R,Na-Bangchang K

更新日期：2010-02-01 00:00:00